Protein Kinase C Modulates Ventilatory Patterning in the Developing Rat
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چکیده
منابع مشابه
Protein kinase C modulates ventilatory patterning in the developing rat.
Protein kinase C (PKC) mediates important components of signal transduction pathways underlying neuronal excitability and modulates respiratory timing mechanisms in adult rats. To determine ventilatory effects of systemic PKC inhibition during development, whole-body plethysmographic recordings were conducted in 2-3-d (n = 11), 5-6-d (n = 19), 10-12-d (n = 14), and 20-21-d-old (n = 14) rat pups...
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The role of protein kinase A (PKA) in the release of amylase from permeabilized pancreatic acini was investigated. Addition of cyclic AMP (cAMP) to permeabilized acini resulted in a potentiation of Ca(2+)-dependent amylase release, shifting the Ca2+ dose/response curve leftwards. As with protein kinase C (PKC) activation, this is due to an increase in the time of active discharge. The effect of...
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ژورنال
عنوان ژورنال: American Journal of Respiratory and Critical Care Medicine
سال: 1999
ISSN: 1073-449X,1535-4970
DOI: 10.1164/ajrccm.159.3.9805041